Metabolomics Analysis Identifies Intestinal Microbiota-Derived Biomarkers of Colonization Resistance in Clindamycin-Treated Mice

BACKGROUND: The intestinal microbiota protect the host against enteric pathogens through a defense mechanism termed colonization resistance. Antibiotics excreted into the intestinal tract may disrupt colonization resistance and alter normal metabolic functions of the microbiota. We used a mouse mode...

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Main Authors: Jump, Robin L. P., Polinkovsky, Alex, Hurless, Kelly, Sitzlar, Brett, Eckart, Kevin, Tomas, Myreen, Deshpande, Abhishek, Nerandzic, Michelle M., Donskey, Curtis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079339/
https://ncbi.nlm.nih.gov/pubmed/24988418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101267
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