Suppression of Gastric Acid Production by Proton Pump Inhibitor Treatment Facilitates Colonization of the Large Intestine by Vancomycin-Resistant Enterococcus spp. and Klebsiella pneumoniae in Clindamycin-Treated Mice

Proton pump inhibitor treatment of clindamycin-treated mice elevated the gastric pH and facilitated the establishment of colonization of the large intestine by vancomycin-resistant Enterococcus spp. (75 to 80%, versus 20 to 25% for saline-treated controls) and Klebsiella pneumoniae (90%, versus 30%...

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Detalhes bibliográficos
Main Authors: Stiefel, Usha, Rao, Agam, Pultz, Michael J., Jump, Robin L. P., Aron, David C., Donskey, Curtis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635221/
https://ncbi.nlm.nih.gov/pubmed/16940078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00522-06
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