Effects of Daptomycin, Linezolid, and Vancomycin on Establishment of Intestinal Colonization with Vancomycin-Resistant Enterococci and Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae in Mice

In mice, vancomycin and linezolid treatment disrupted the anaerobic intestinal microflora, based on denaturing gradient gel electrophoresis analysis, and promoted colonization by Klebsiella pneumoniae and vancomycin-resistant enterococci. However, the effects varied depending on dose and duration of...

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Bibliographic Details
Main Authors: Pultz, Nicole J., Stiefel, Usha, Donskey, Curtis J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196280/
https://ncbi.nlm.nih.gov/pubmed/16048971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3513-3516.2005
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