Effect of Surotomycin, a Novel Cyclic Lipopeptide Antibiotic, on Intestinal Colonization with Vancomycin-Resistant Enterococci and Klebsiella pneumoniae in Mice

Surotomycin (formerly called CB-183,315) is a novel, orally administered cyclic lipopeptide antibacterial in development for the treatment of Clostridium difficile infection (CDI) that has potent activity against vancomycin-resistant enterococci (VRE) but limited activity against Gram-negative bacil...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Deshpande, Abhishek, Hurless, Kelly, Cadnum, Jennifer L., Chesnel, Laurent, Gao, Lihong, Chan, Luisa, Kundrapu, Sirisha, Polinkovsky, Alexander, Donskey, Curtis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879352/
https://ncbi.nlm.nih.gov/pubmed/26976870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02904-15
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