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Effect of Fidaxomicin versus Vancomycin on Susceptibility to Intestinal Colonization with Vancomycin-Resistant Enterococci and Klebsiella pneumoniae in Mice

The use of oral vancomycin or metronidazole for treatment of Clostridium difficile infection (CDI) may promote colonization by health care-associated pathogens due to disruption of the intestinal microbiota. Because the macrocyclic antibiotic fidaxomicin causes less alteration of the intestinal micr...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Deshpande, Abhishek, Hurless, Kelly, Cadnum, Jennifer L., Chesnel, Laurent, Gao, Lihong, Chan, Luisa, Kundrapu, Sirisha, Polinkovsky, Alexander, Donskey, Curtis J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914684/
https://ncbi.nlm.nih.gov/pubmed/27090175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02590-15
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