A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

Many organs with a high cell turnover (for example, skin, intestine and blood) are composed of short-lived cells that require continuous replenishment by somatic stem cells(1,2). Ageing results in the inability of these tissuesto maintain homeostasis and it is believed that somatic stem-cell ageing...

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Main Authors: Florian, Maria Carolina, Nattamai, Kalpana J., Dörr, Karin, Marka, Gina, Überle, Bettina, Vas, Virag, Eckl, Christina, Andrä, Immanuel, Schiemann, Matthias, Oostendorp, Robert A. J., Scharffetter-Kochanek, Karin, Kestler, Hans Armin, Zheng, Yi, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078992/
https://ncbi.nlm.nih.gov/pubmed/24141946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12631
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