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Aging of the Microenvironment Influences Clonality in Hematopoiesis

The mechanisms of the age-associated exponential increase in the incidence of leukemia are not known in detail. Leukemia as well as aging are initiated and regulated in multi-factorial fashion by cell-intrinsic and extrinsic factors. The role of aging of the microenvironment for leukemia initiation/...

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Detalhes bibliográficos
Main Authors: Vas, Virag, Senger, Katharina, Dörr, Karin, Niebel, Anja, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412859/
https://ncbi.nlm.nih.gov/pubmed/22879906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042080
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