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A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

A diverse array of tumor targeting agents ranging in size from peptides to nanoparticles is currently under development for applications in cancer imaging and therapy. However, it remains largely unclear how size differences among these molecules influence their targeting properties. Here we develop...

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Detalhes bibliográficos
Main Authors: Schmidt, Michael M., Wittrup, K. Dane
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078872/
https://ncbi.nlm.nih.gov/pubmed/19825804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0195
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