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PRACTICAL THEORETIC GUIDANCE FOR THE DESIGN OF TUMOR-TARGETING AGENTS
Theoretical analyses of targeting agent pharmacokinetics provides specific guidance with respect to desirable design objectives such as agent size, affinity, and target antigen. These analyses suggest that IgG-sized macromolecular constructs exhibit the most favorable balance between systemic cleara...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978464/ https://ncbi.nlm.nih.gov/pubmed/22230572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-396962-0.00010-0 |
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