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Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma

The primary cilium acts as a cellular antenna, transducing diverse signaling pathways, and recent evidence suggests that primary cilia are important in development and cancer. However, a role for cilia in normal muscle development and rhabdomyosarcoma (RMS) has not been explored. Here we implicate p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fu, Wenxiang, Asp, Patrik, Canter, Brian, Dynlacht, Brian David
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078804/
https://ncbi.nlm.nih.gov/pubmed/24927541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323265111
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