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Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

Polycomb group (PcG) proteins play important roles in repressing lineage-specific genes and maintaining the undifferentiated state of mouse embryonic stem cells (mESCs). However, how PcG proteins are recruited to their target genes is largely unknown. Here, we show that the H3K36-specific histone de...

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Detalhes bibliográficos
Main Authors: He, Jin, Shen, Li, Wan, Ma, Taranova, Olena, Wu, Hao, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078788/
https://ncbi.nlm.nih.gov/pubmed/23502314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2702
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