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Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells

The recruitment of Polycomb repressive complex 2 (PRC2) to gene promoters is critical for its function in repressing gene expression in murine embryonic stem cells (mESCs). However, previous studies have demonstrated that although the expression of early lineage-specific genes is largely repressed,...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Aljazi, Mohammad B., Gao, Yuen, Wu, Yan, Mias, George I., He, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578752/
https://ncbi.nlm.nih.gov/pubmed/33103084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101646
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