Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators

Polycomb Repressor Complexes (PRCs) are important regulators of embryogenesis. In embryonic stem (ES) cells many genes that regulate subsequent stages in development are enriched at their promoters for PRC1, PRC2 and Ser 5-phosphorylated RNA Polymerase II (RNAP), and contain domains of ‘bivalent’ ch...

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Bibliografiska uppgifter
Huvudupphovsmän: Landeira, David, Sauer, Stephan, Poot, Raymond, Dvorkina, Maria, Mazzarella, Luca, Jørgensen, Helle F., Pereira, C. Filipe, Leleu, Marion, Piccolo, Francesco M., Spivakov, Mikhail, Brookes, Emily, Pombo, Ana, Fisher, Cynthia, Skarnes, William C., Snoek, Tim, Bezstarosti, Karel, Demmers, Jeroen, Klose, Robert J., Casanova, Miguel, Tavares, Ligia, Brockdorff, Neil, Merkenschlager, Matthias, Fisher, Amanda G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572404/
https://ncbi.nlm.nih.gov/pubmed/20473294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2065
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