Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas

Cholestatic liver injury appears to result from the induction of hepatocyte apoptosis by toxic bile salts such as glycochenodeoxycholate (GCDC). Previous studies from this laboratory indicate that cathepsin B is a downstream effector protease during the hepatocyte apoptotic process. Because caspases...

Descripció completa

Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Faubion, William A., Guicciardi, M. Eugenia, Miyoshi, Hideyuki, Bronk, Steven F., Roberts, Patricia J., Svingen, Phyllis A., Kaufmann, Scott H., Gores, Gregory J.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 1999
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9884343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4765
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!