Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice

A novel approach was employed to assess the contribution of the renin-angiotensin system (RAS) to obstructive nephropathy in neonatal mice having zero to four functional copies of the angiotensinogen gene (Agt). Two-day-old mice underwent unilateral ureteral obstruction (UUO) or sham operation; 28 d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Fern, Robert J., Yesko, Christine M., Thornhill, Barbara A., Kim, Hyung-Suk, Smithies, Oliver, Chevalier, Robert L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1999
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC407859/
https://ncbi.nlm.nih.gov/pubmed/9884332
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares