Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function.

Antzeko izenburuak

• The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.
  nork: Skolnik, E Y, et al.
  Argitaratua: (1993)
• Peptide Bicycles that Inhibit the Grb2 SH2 Domain
  nork: Quartararo, Justin S., et al.
  Argitaratua: (2012)
• Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins.
  nork: Neumeister, E N, et al.
  Argitaratua: (1995)
• Serine Phosphorylation Proximal to Its Phosphotyrosine Binding Domain Inhibits Insulin Receptor Substrate 1 Function and Promotes Insulin Resistance
  nork: Liu, Yan-Fang, et al.
  Argitaratua: (2004)
• Binding of the Grb2 SH2 domain to phosphotyrosine motifs does not change the affinity of its SH3 domains for Sos proline-rich motifs.
  nork: Cussac, D, et al.
  Argitaratua: (1994)