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Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.

She is a widely expressed adapter protein that plays an important role in signaling via a variety of cell surface receptors and has been implicated in coupling the stimulation of growth factor, cytokine, and antigen receptors to the Ras signaling pathway. She interacts with several tyrosine-phosphor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zhou, M M, Meadows, R P, Logan, T M, Yoon, H S, Wade, W S, Ravichandran, K S, Burakoff, S J, Fesik, S W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7544002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7784
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