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MeCP2 Repression of G9a in Regulation of Pain and Morphine Reward

Opioids are commonly used for pain relief, but their strong rewarding effects drive opioid misuse and abuse. How pain affects the liability of opioid abuse is unknown at present. In this study, we identified an epigenetic regulating cascade activated by both pain and the opioid morphine. Both persis...

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Hlavní autoři: Zhang, Zhi, Tao, Wenjuan, Hou, Yuan-Yuan, Wang, Wei, Kenny, Paul J., Pan, Zhizhong Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078085/
https://ncbi.nlm.nih.gov/pubmed/24990928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4194-13.2014
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