Persistent Pain Facilitates Response to Morphine Reward by Downregulation of Central Amygdala GABAergic Function

Opioid-based analgesics are widely used for treating chronic pain, but opioids are highly addictive when repeatedly used because of their strong rewarding effects. In recent years, abuse of prescription opioids has dramatically increased, including incidences of misuse of opioid drugs prescribed for...

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Autores principales: Zhang, Zhi, Tao, Wenjuan, Hou, Yuan-Yuan, Wang, Wei, Lu, Yun-Gang, Pan, Zhizhong Z
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104345/
https://ncbi.nlm.nih.gov/pubmed/24686896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.77
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