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MeCP2 Repression of G9a in Regulation of Pain and Morphine Reward

Opioids are commonly used for pain relief, but their strong rewarding effects drive opioid misuse and abuse. How pain affects the liability of opioid abuse is unknown at present. In this study, we identified an epigenetic regulating cascade activated by both pain and the opioid morphine. Both persis...

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Detalles Bibliográficos
Main Authors: Zhang, Zhi, Tao, Wenjuan, Hou, Yuan-Yuan, Wang, Wei, Kenny, Paul J., Pan, Zhizhong Z.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078085/
https://ncbi.nlm.nih.gov/pubmed/24990928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4194-13.2014
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