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CHIP Regulates Osteoclast Formation through Promoting TRAF6 Protein Degradation

OBJECTIVE: Carboxyl terminus of Hsp70-interacting protein (CHIP or STUB1) is an E3 ligase and regulates the stability of several proteins which are involved in tumor growth and metastasis. However, the role of CHIP in bone growth and bone remodeling in vivo has not been reported. The objective of th...

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Detalhes bibliográficos
Main Authors: Li, Shan, Shu, Bing, Zhang, Yanquan, Li, Jia, Guo, Junwei, Wang, Yinyin, Ren, Fangli, Xiao, Guozhi, Chang, Zhijie, Chen, Di
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077927/
https://ncbi.nlm.nih.gov/pubmed/24578159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38521
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