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MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell
MIR34A (microRNA 34a) is a tumor suppressor gene, but how it regulates chemotherapy response and resistance is not completely understood. Here, we show that the microRNA MIR34A-dependent high mobility group box 1 (HMGB1) downregulation inhibits autophagy and enhances chemotherapy-induced apoptosis i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077883/ https://ncbi.nlm.nih.gov/pubmed/24418846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27418 |
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