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MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell

MIR34A (microRNA 34a) is a tumor suppressor gene, but how it regulates chemotherapy response and resistance is not completely understood. Here, we show that the microRNA MIR34A-dependent high mobility group box 1 (HMGB1) downregulation inhibits autophagy and enhances chemotherapy-induced apoptosis i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Ke, Huang, Jun, Xie, Min, Yu, Yan, Zhu, Shan, Kang, Rui, Cao, Lizhi, Tang, Daolin, Duan, Xuanchu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077883/
https://ncbi.nlm.nih.gov/pubmed/24418846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27418
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