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Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids

SQSTM1/p62 (sequestosome 1) is a multifunctional signaling molecule, involved in a variety of cellular pathways. SQSTM1 is one of the best-known autophagic substrates, and is therefore widely used as an indicator of autophagic degradation. Here we report that the expression level of SQSTM1 can be re...

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Detalhes bibliográficos
Main Authors: Sahani, Mayurbhai Himatbhai, Itakura, Eisuke, Mizushima, Noboru
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077882/
https://ncbi.nlm.nih.gov/pubmed/24394643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27344
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