Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

Autophagy plays important roles in many biological processes, but our understanding of the mechanisms regulating stem cells by autophagy is limited. Interpretations of earlier studies of autophagy using knockouts of single genes are confounded by accumulating evidence for other functions of many aut...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Wang, Chenran, Chen, Song, Yeo, Syn, Karsli-Uzunbas, Gizem, White, Eileen, Mizushima, Noboru, Virgin, Herbert W., Guan, Jun-Lin
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2016
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772497/
https://ncbi.nlm.nih.gov/pubmed/26929451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507023
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