Nalaganje...
Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
Autophagy, a lysosomal degradation pathway, plays crucial roles in health and disease. p62/SQSTM1 (hereafter p62) is an autophagy adaptor protein that can shuttle ubiquitinated cargo for autophagic degradation. Here, we show that upregulating the Drosophila p62 homolog ref(2)P/dp62, starting in midl...
Shranjeno v:
| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688777/ https://ncbi.nlm.nih.gov/pubmed/31340141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.070 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|