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Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate

Incorporation of degradable moieties into synthetic hydrogels has greatly increased the utility of these three-dimensional matrices for in vitro cell culture as well as tissue engineering applications. A common method for introducing degradability is the inclusion of oligopeptides sensitive to cleav...

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Detalhes bibliográficos
Main Authors: Leight, Jennifer L., Alge, Daniel L., Maier, Andrew J., Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077845/
https://ncbi.nlm.nih.gov/pubmed/23830581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.06.023
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