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Osteogenic differentiation of human mesenchymal stem cells on α5 integrin binding peptide hydrogels is dependent on substrate elasticity

The extracellular matrix plays a crucial role in controlling human mesenchymal stem cell (hMSC) biology including differentiation, and α5β1 integrin signaling plays an important role during osteogenic differentiation of hMSCs. Here, peptide-functionalized hydrogels were used to examine the role of α...

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Detalhes bibliográficos
Main Authors: Gandavarapu, Navakanth R., Alge, Daniel L., Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960008/
https://ncbi.nlm.nih.gov/pubmed/24660057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3BM60149H
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