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Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

Extracellular proteolysis mediates tissue homeostasis. In cancer, altered proteolysis leads to unregulated tumor growth, tissue remodeling, inflammation, tissue invasion, and metastasis. The matrix metalloproteinases (MMPs) represent the most prominent family of proteinases associated with tumorigen...

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Detalhes bibliográficos
Main Authors: Kessenbrock, Kai, Plaks, Vicki, Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862057/
https://ncbi.nlm.nih.gov/pubmed/20371345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.015
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