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The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells?

Cancer stem cells (CSCs) are tumor cells that have the principal properties of self-renewal, clonal tumor initiation capacity and clonal long-term repopulation potential. CSCs reside in niches, which are anatomically distinct regions within the tumor microenvironment. These niches maintain the princ...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Plaks, Vicki, Kong, Niwen, Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355577/
https://ncbi.nlm.nih.gov/pubmed/25748930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.02.015
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