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Central leptin replacement enhances chemorespiratory responses in leptin-deficient mice independent of changes in body weight
Previous studies showed that leptin-deficient (ob/ob) mice develop obesity and impaired ventilatory responses to CO(2) ([Formula: see text] − CO(2)). In this study, we examined if leptin replacement improves chemorespiratory responses to hypercapnia (7 % CO(2)) in ob/ob mice and if these effects wer...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077668/ https://ncbi.nlm.nih.gov/pubmed/22585210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1111-1 |
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