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Leptin reverses hyperglycemia and hyperphagia in insulin deficient diabetic rats by pituitary-independent central nervous system actions

The hypothalamic-pituitary-adrenal (HPA) axis has been postulated to play a major role in mediating the antidiabetic effects of leptin. We tested if the pituitary is essential for the chronic central nervous system mediated actions of leptin on metabolic and cardiovascular function in insulin-depend...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: da Silva, Alexandre A., Hall, John E., do Carmo, Jussara M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708697/
https://ncbi.nlm.nih.gov/pubmed/29190687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184805
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