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Activation of the brain melanocortin system is required for leptin-induced modulation of chemorespiratory function

Melanocortin receptors (MC3/4R) mediate most of the metabolic and cardiovascular actions of leptin. AIM: here we tested if MC4R also contributes to leptin’s effects on respiratory function. METHODS: after control measurements, male Holtzman rats received daily microinjections of leptin, SHU9119 (MC3...

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Detalhes bibliográficos
Publicado no:Acta Physiol (Oxf)
Main Authors: Bassi, M, Nakamura, NB, Furuya, WI, Colombari, DSA, Menani, JV, do Carmo, JM, da Silva, AA, Hall, JE, Colombari, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362918/
https://ncbi.nlm.nih.gov/pubmed/25207799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12394
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