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Structural and functional studies of the 252 kDa nucleoporin ELYS reveal distinct roles for its three tethered domains
In metazoa, the nuclear envelope (NE), together with the embedded nuclear pore complexes (NPCs), breaks down and reassembles during cell division. It is suggested that ELYS, a nucleoporin, binds to chromatin in an initial step of postmitotic NPC assembly and subsequently recruits the essential Y-sub...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077343/ https://ncbi.nlm.nih.gov/pubmed/23499022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.02.006 |
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