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Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor

Cell-binding and internalization studies on neuronal and non-neuronal cells have demonstrated that the 37-kDa/67-kDa laminin receptor (LRP/LR) acts as the receptor for the cellular prion protein (PrP). Here we identify direct and heparan sulfate proteoglycan (HSPG)-dependent interaction sites mediat...

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Udgivet i:EMBO J
Principais autores: Hundt, Christoph, Peyrin, Jean-Michel, Haïk, Stéphane, Gauczynski, Sabine, Leucht, Christoph, Rieger, Roman, Riley, Maria Louise, Deslys, Jean-Philippe, Dormont, Dominique, Lasmézas, Corinne Ida, Weiss, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.21.5876
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