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Structural and functional studies of the 252 kDa nucleoporin ELYS reveal distinct roles for its three tethered domains

In metazoa, the nuclear envelope (NE), together with the embedded nuclear pore complexes (NPCs), breaks down and reassembles during cell division. It is suggested that ELYS, a nucleoporin, binds to chromatin in an initial step of postmitotic NPC assembly and subsequently recruits the essential Y-sub...

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Bibliographic Details
Main Authors: Bilokapic, Silvija, Schwartz, Thomas U.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077343/
https://ncbi.nlm.nih.gov/pubmed/23499022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.02.006
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