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Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores

How individual nucleoporins (Nups) perform their role in nuclear pore structure and function is largely unknown. In this study, we examined the structure of purified Nup170 to obtain clues about its function. We show that Nup170 adopts a crescent moon shape with two structurally distinct and separab...

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Detalhes bibliográficos
Main Authors: Flemming, Dirk, Sarges, Phillip, Stelter, Philipp, Hellwig, Andrea, Böttcher, Bettina, Hurt, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700402/
https://ncbi.nlm.nih.gov/pubmed/19414606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810016
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