Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression

BACKGROUND: High-quality expression data are required to investigate the biological effects of microRNAs (miRNAs). The goal of this study was, first, to assess the quality of miRNA expression data based on microarray technologies and, second, to consolidate it by applying a novel normalization metho...

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Detalhes bibliográficos
Main Authors: Sewer, Alain, Gubian, Sylvain, Kogel, Ulrike, Veljkovic, Emilija, Han, Wanjiang, Hengstermann, Arnd, Peitsch, Manuel C, Hoeng, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077261/
https://ncbi.nlm.nih.gov/pubmed/24886675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-302
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