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Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G(2)-M arrest and apoptosis in HeLa cells
AIM: To identify a novel coumarin analogue with the highest anticancer activity and to further investigate its anticancer mechanisms. METHODS: The viability of cancer cells was investigated using the MTT assay. The cell cycle progression was evaluated using both flow cytometric and Western blotting...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077132/ https://ncbi.nlm.nih.gov/pubmed/22266726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.176 |
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