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Effect of SP600125 on the mitotic spindle in HeLa Cells, leading to mitotic arrest, endoreduplication and apoptosis

BACKGROUND: The JNK inhibitor SP600125 strongly inhibits cell proliferation in many human cancer cells by blocking mitosis progression and inducing cell death. Despite, all this study, the mechanism by which SP600125 inhibits mitosis-related effects in human cervical cells (HeLa cells) remains uncle...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cytogenet
Päätekijät: Mili, Donia, Abid, Kaouthar, Rjiba, Imed, Kenani, Abderraouf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123282/
https://ncbi.nlm.nih.gov/pubmed/27924151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0296-y
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