NMK-TD-100, a Novel Microtubule Modulating Agent, Blocks Mitosis and Induces Apoptosis in HeLa Cells by Binding to Tubulin

Thiadiazoles are one of the most widely utilized agents in medicinal chemistry, having a wide range of pharmacologic activity. Microtubules (MTs) have always remained a sought-after target in rapidly proliferating cancer cells. We screened for the growth inhibitory effect of synthetic 5-(3-indolyl)-...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Surela, Kumar, N. Maruthi, Ganguli, Arnab, Tantak, Mukund P., Kumar, Dalip, Chakrabarti, Gopal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792137/
https://ncbi.nlm.nih.gov/pubmed/24116100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076286
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