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Targeted shRNA screening identified critical roles of pleckstrin-2 in erythropoiesis

Differentiation of erythroblasts to mature red blood cells involves dynamic changes of the membrane and cytoskeleton networks that are not fully characterized. Using a mouse fetal liver erythroblast culture system and a targeted shRNA functional screening strategy, we identified a critical role of p...

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Detalhes bibliográficos
Main Authors: Zhao, Baobing, Keerthivasan, Ganesan, Mei, Yang, Yang, Jing, McElherne, James, Wong, Piu, Doench, John G., Feng, Gang, Root, David E., Ji, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077076/
https://ncbi.nlm.nih.gov/pubmed/24747950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.105809
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