Early lethality of shRNA-transgenic pigs due to saturation of microRNA pathways

RNA interference (RNAi) is considered as a potential modality for clinical treatment and anti-virus animal breeding. Here, we investigate the feasibility of inhibiting classical swine fever virus (CSFV) replication by short hairpin RNA (shRNA) in vitro and in vivo. We generate four different shRNA-p...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Dai, Zhen, Wu, Rong, Zhao, Yi-cheng, Wang, Kan-kan, Huang, Yong-ye, Yang, Xin, Xie, Zi-cong, Tu, Chang-chun, Ouyang, Hong-sheng, Wang, Tie-dong, Pang, Da-xin
Format: Artigo
Idioma:Inglês
Publicat: Zhejiang University Press 2014
Matèries:
Genetics and Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076603/
https://ncbi.nlm.nih.gov/pubmed/24793764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1400001
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars