Transgenic shRNA pigs reduce susceptibility to foot and mouth disease virus infection

Foot-and-mouth disease virus (FMDV) is an economically devastating viral disease leading to a substantial loss to the swine industry worldwide. A novel alternative strategy is to develop pigs that are genetically resistant to infection. Here, we produce transgenic (TG) pigs that constitutively expre...

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Vydáno v:eLife
Hlavní autoři: Hu, Shengwei, Qiao, Jun, Fu, Qiang, Chen, Chuangfu, Ni, Wei, Wujiafu, Sai, Ma, Shiwei, Zhang, Hui, Sheng, Jingliang, Wang, Pengyan, Wang, Dawei, Huang, Jiong, Cao, Lijuan, Ouyang, Hongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2015
Témata:
Microbiology and Infectious Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502569/
https://ncbi.nlm.nih.gov/pubmed/26090904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06951
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