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Inhibition of foot-and-mouth disease virus replication in vitro and in vivo by small interfering RNA

By using bioinformatics computer programs, all foot-and-mouth disease virus (FMDV) genome sequences in public-domain databases were analyzed. Based on the results of homology analysis, 2 specific small interfering RNA (siRNA) targeting homogenous 3D and 2B1 regions of 7 serotypes of FMDV were prepar...

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Detalhes bibliográficos
Main Authors: Pengyan, Wang, Yan, Ren, Zhiru, Guo, Chuangfu, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515107/
https://ncbi.nlm.nih.gov/pubmed/18652701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-86
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