Endoplasmic Reticulum Stress Mediates Amyloid β Neurotoxicity via Mitochondrial Cholesterol Trafficking

Disrupted cholesterol homeostasis has been reported in Alzheimer disease and is thought to contribute to disease progression by promoting amyloid β (Aβ) accumulation. In particular, mitochondrial cholesterol enrichment has been shown to sensitize to Aβ-induced neurotoxicity. However, the molecular m...

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Dades bibliogràfiques
Autors principals: Barbero-Camps, Elisabet, Fernández, Anna, Baulies, Anna, Martinez, Laura, Fernández-Checa, Jose C., Colell, Anna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2014
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076561/
https://ncbi.nlm.nih.gov/pubmed/24815354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.014
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