Endoplasmic Reticulum Stress Mediates Amyloid β Neurotoxicity via Mitochondrial Cholesterol Trafficking

Disrupted cholesterol homeostasis has been reported in Alzheimer disease and is thought to contribute to disease progression by promoting amyloid β (Aβ) accumulation. In particular, mitochondrial cholesterol enrichment has been shown to sensitize to Aβ-induced neurotoxicity. However, the molecular m...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Barbero-Camps, Elisabet, Fernández, Anna, Baulies, Anna, Martinez, Laura, Fernández-Checa, Jose C., Colell, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2014
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076561/
https://ncbi.nlm.nih.gov/pubmed/24815354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.014
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi