Endoplasmic Reticulum Stress Mediates Amyloid β Neurotoxicity via Mitochondrial Cholesterol Trafficking

Disrupted cholesterol homeostasis has been reported in Alzheimer disease and is thought to contribute to disease progression by promoting amyloid β (Aβ) accumulation. In particular, mitochondrial cholesterol enrichment has been shown to sensitize to Aβ-induced neurotoxicity. However, the molecular m...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Barbero-Camps, Elisabet, Fernández, Anna, Baulies, Anna, Martinez, Laura, Fernández-Checa, Jose C., Colell, Anna
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2014
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076561/
https://ncbi.nlm.nih.gov/pubmed/24815354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.014
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы