Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress

Alcoholic liver disease (ALD) is a major cause of chronic liver disease and a growing health concern in theworld. While the pathogenesis of ALD is poorly characterized key players identified in experimental models and patients, such as perturbations in mitochondrial structure and function, selective...

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Bibliografische gegevens
Hoofdauteurs: Montserrat Marí, Albert Morales, Anna Colell, Carmen García-Ruiz, Jose C. Fernández-Checa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2014-01-01
Reeks:Redox Biology
Onderwerpen:
Mitochondrial respiratory chain
Mitochondrial cholesterol
Lipotoxicity
ER stress
Mitochondrial GSH
Acid sphingomyelinase
Online toegang:http://www.sciencedirect.com/science/article/pii/S2213231714001049
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