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Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells

Autophagy is a lysosomal bulk degradation pathway for cytoplasmic cargo, such as long-lived proteins, lipids, and organelles. Induced upon nutrient starvation, autophagic degradation is accomplished by the concerted actions of autophagy-related (ATG) proteins. Here we demonstrate that two ATGs, huma...

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Autori principali: Pfisterer, Simon G., Bakula, Daniela, Frickey, Tancred, Cezanne, Alice, Brigger, Daniel, Tschan, Mario P., Robenek, Horst, Proikas-Cezanne, Tassula
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076084/
https://ncbi.nlm.nih.gov/pubmed/24776541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M046359
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