Defining regulatory and phosphoinositide-binding sites in the human WIPI-1 β-propeller responsible for autophagosomal membrane localization downstream of mTORC1 inhibition

BACKGROUND: Autophagy is a cytoprotective, lysosomal degradation system regulated upon induced phosphatidylinositol 3-phosphate (PtdIns(3)P) generation by phosphatidylinositol 3-kinase class III (PtdIns3KC3) downstream of mTORC1 inhibition. The human PtdIns(3)P-binding β-propeller protein WIPI-1 acc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gaugel, Anja, Bakula, Daniela, Hoffmann, Anneliese, Proikas-Cezanne, Tassula
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543385/
https://ncbi.nlm.nih.gov/pubmed/23088497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-7-16
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak